When Kevin O'Neil, a realtor to the stars, is accused of brutally murdering his beautiful wife Caitlin, he hires the firm of Trott, Nicholson, Tuller & Gaines. Spurred on by the court TV show, American Crime, the media have all but convicted him and are out for blood as is the prosecutor. But the lawyers at TNT&G use state-of-the-art forensic interpretation, jury consultants, mock juries, experts, and masterful media spin to defend Kevin. All techniques may be successful as long as the attorneys can cope with the new evidence that seems to keep turning up.

TNT&G takes the case of a young female college student claiming self-defense in the death of a famous music producer who has a history of abusing women. Soon the attorneys believe they might be defending a cold-blooded murderer because she changes her testimony to explain each new, incriminating piece of evidence that is found.

TNT&G goes to Orange County when a bartender, who is employed at a restaurant co-owned by Ron, is accused of killing a runaway bride. Ron's certainty of a win begins to wane, however, when the team encounters the culture shock of Orange County.

TNT&G represents a teenaged outcast with a history of antisocial behavior who has been accused of the ritualistic murder of the high school bully.

TNT&G takes the case of Ron Trott's former lover who claims she murdered her teenaged son in self-defense.

A babysitter is blamed for the death of a child and forced to confess. Despite the way the confession was obtained it was allowed in the trial.