Ian proposes to Susan. The Scavo pizzeria prepares for its grand opening. Mike visits a hypnotherapist in hopes of remembering Monique. Gabrielle's romantically interested in a lawyer, but he's working for Zach who wants her for himself. Bree is hospitalized after a fall, after being tricked to climb on a ladder to retrieve Monique's teeth.

A tornado comes to Wisteria Lane, forcing residents into basements, cellars and safe rooms, and destroying homes and lives. Meanwhile, Susan ends up at the hospital after falling down the stairs.