Younger Picasso finds respite from his strained marriage with Olga in the arms of his newest muse: Marie-Thérèse Walter. However, their romance is short-lived, cause soon he crosses paths with Dora Maar. Meanwhile, Françoise Gilot defies Older Picasso and pursues her artistic goals.

After Françoise Gilot leaves him, Pablo finds companionship with a new woman. In near seclusion, Pablo obsesses over creating the perfect painting. Meanwhile, Françoise struggles to escape Picasso's shadow even after remarrying and moving to the US.