Diagnosed with schizophrenia, Owen is the black sheep of the wealthy Milgrim clan. After losing his job, he enrolls in an experimental drug trial.

When her pilfered stash of pills runs out, troubled Annie tries to quit -- but ends up blackmailing her way into the Neberdine study.

Muramoto notices irregularities in Annie and Owen's data. He questions Owen, who recalls the worst night of his life: his brother's engagement party.

After taking the B pill, Annie and Owen find themselves on 1980s Long Island entangled in a strange caper involving a lemur.

Annia and Ellia continue their quest, and Owen's mafioso father pressures him to protect the family. Greta counsels a bereaved Gertie.