Zaccardo, head of the Section, informs Ardenzi and Sabatini of an upcoming very important operation to capture a fugitive in a Roma camp in the Capital. They must prepare and carry it out as best they can. This obviously while emergencies arrive at the Police Headquarters. / Today is the day of the blitz. The team is finalizing the final preparations but the police headquarters receives a report of a woman run over on Lungo Tevere, and moreover the daughter of a repentant.

While at the police station Claudio Sabatini is looking for a way to free Bradic, who is being held awaiting questioning, without arousing the suspicions of his colleagues, Ardenzi and Sandro are dealing with the case of a Pakistani girl stoned to death in the street and Isabella is dealing with her first serious friction with her boyfriend Giulio who ends up slapping her with serious consequences. / Bradic's death at the police station and at the hands of Marcello, forces the commissioner to put the young policeman under investigation and for this reason Oliviero, feeling misunderstood and unjustly accused, runs away and disappears. Ardenzi is worried about the boy, he wants to find him and it is his job to clarify the dynamics of the facts; Claudio Sabatini also needs to find Marcello.

The death of Marcello has shocked the entire team but the worst blow was suffered by Roberto who feels responsible for the boy's disappearance and is now determined to understand what happened. In the meantime, Sandro and Giacomo discover a prostitution ring run by chinese where underage girls are enslaved; while Isabella and Valeria manage to save Giulia, a woman mistreated by her husband, who for the love of her daughter finds the courage to report him... but for Isa, a champion of mistreated women, the real troubles begin now: on her PC, in fact, an order to stop from an anonymous but very threatening sender arrives. / Ardenzi, following the notice of investigation, appears before the judge with his lawyer and discovers that he is being investigated for incitement to suicide.

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Isabella is suspended for beating Cristina's murderer after his arrest. Sandro and Ardenzi follow Sabatini and discover that he is meeting with Lele Bianchi, a customs officer from the port of Civitavecchia already known for previous drug dealing. / Zaccardo informs Ardenzi that Sabatini will be in charge of the section. Ardenzi interrogates Lele Bianchi to try to obtain evidence against Sabatini, but before he can obtain any information, Bianchi is released from prison.

On the day of Valeria's and Zaccardo's wedding, he informs Ardenzi of his transfer to the Viterbo police station. The team therefore has little time to frame Sabatini: they must find the gun that killed Bradic and Clerici as soon as possible and foil the major drug trafficking that Claudio is completing with the help of Vanessa. Sandro finally discovers Sabatini's garage where the gun is kept, but this discovery could be very dangerous. / Sandro, seriously injured by Vanessa, is taken to the hospital in serious condition. Ardenzi recovers Sabatini's gun and can finally prove his guilt. Claudio, now hunted, wants to carry out the last drug trafficking and then flee abroad.