The 118 responds to debris from a meteor shower crashing into an apartment building and a deadly fire caused by a hazardous waste truck crash inside a tunnel. Meanwhile, Hen struggles with guilt over her ambulance accident, Bobby introduces Eddie to an old friend to help with his anger and Maddie receives an urgent call for help.

Holiday-themed incidents include a shopper pushed over the edge, a woman who is literally having a "Blue Christmas" and a luggage handler accident on a tarmac; Maddie revisits her past to embrace her future; Bobby receives shocking news.

Athena investigates a robbery at a gas station that takes an unexpected turn when the would-be victim turns the tables on her assailant. Meanwhile, Bobby and the 126 race to rescue a novice diver who panics while in a shark cage, and a house sitter terrified of spiders. Then, Eddie reaches his breaking point, Chimney returns to the 118 and Maddie shares some news with Buck, who realizes he has to come clean with Taylor.

Athena and Bobby set off on their honeymoon cruise, but when duty calls, their vacation is put on hold. Meanwhile, a fighter jet traps a civilian, and an unusual incident leaves a couple stuck together.

The disastrous cruise continues when Bobby and Athena respond to the ship's explosion, racing to aid injured passengers. Meanwhile, Hen questions her instincts in a life-taking call and grows concerned about Athena and Bobby's whereabouts.