The 118 race to save a man under siege by his high-tech smart home, and a yoga teacher who has lost her vision. Athena hunts down a bank robber disguised by Covid protocols. Meanwhile, Buck confides in Maddie, Hen clashes with her antagonizing medical school lab partner and members of the 118's crew prep for an out-of-state mission.

The 118 are called to the tarmac when a flight attendant reaches her limit with her flight's passengers. Athena discovers that quarantine has pushed a couple to their breaking point. Meanwhile, Eddie worries Christopher will not accept him dating, Buck reconnects with an old flame and finds himself in the middle of Albert's new relationship and Maddie and Chimney make a big decision about their baby.

Athena and the 118 race to save lives after a drunk driver causes a deadly pile-up on the freeway. Meanwhile, Maddie goes into labor and Hen and Karen are devastated as they prepare their foster daughter, Nia, to be reunited with her birth mother.

The 118 responds to a series of calls dealing with parents and their children, including a disastrous birthday party thrown by a mommy blogger. Meanwhile, Athena and Michael talk to May about her past suicide attempt, Chimney and Maddie adjust to life with their newborn, and Hen and Karen are emotionally shattered as their foster daughter, Nia, is reunited with her birth mother.

Hen fears for Karen's life when an explosion rocks her science lab on the day she brings Denny to work with her.

Hen and Karen welcome a new addition to their family, while a call unfolds involving a person’s limb that’s taken on a mind of its own. Meanwhile, Eddie and Marisol take a closer look at their relationship, and Buck navigates his new feelings.

Maddie and Athena investigate a case surrounding an abducted mother and child as Hen and Karen learn more about Mara’s family history. Meanwhile, Eddie grapples with unresolved feelings for someone from his past.