When the team responds to an apartment fire, Captain Pruitt takes a hit, the future of the station’s leadership is in jeopardy and firefighter Andy Herrera is forced to step up. Meanwhile, new recruit Ben Warren is trading in the scalpel for a fresh start as a firefighter, but it hasn’t been easy.

Miranda Bailey visits Ben at work, meeting his new co-workers for the first time. While most of the team responds to a motor vehicle accident involving an electrical danger, Andy and Maya are paired up to go on their first stakeout.

Ryan tags along to a disaster drill training at Station 19 where he and Jack get competitive. Captain Pruitt’s health weakens and Andy is sticking by his side. Meanwhile, both the firehouse crew and police department respond to a strip mall fire, forcing Jack and Ryan to work together.

Ben reaches a new milestone as a rookie and, as is tradition, receives something from the crew. Chief Ripley holds final interviews for the role of captain but is interrupted when the team is called to a massive skyscraper fire, causing several lives to hang in the balance.

Lives hang in the balance as the members of Station 19 continue to fight a raging inferno inside a skyscraper. Meanwhile, Pruitt’s health is in grave danger at Grey Sloan; and a seasoned firefighter with a mysterious past arrives at Station 19, leaving everyone to wonder what the future holds.

Captain Sullivan continues his efforts to bring together the fire and police departments by hosting a training seminar that does not go as planned. Meanwhile, Ben and Miranda have an honest conversation about their marriage, leading Miranda to make a tough decision about their future.

After a car crashes into Joe’s Bar, Andy and Sullivan lead the team of firefighters as they work to rescue their fellow crewmates Ben and Pruitt, Grey Sloan doctors and interns, and bar patrons before the building comes crumbling down.

The crossover continues on Grey's Anatomy S16E10 Help Me Through the Night (II).

The Station 19 crew responds to a drunk driver scene. Meanwhile, Dean receives advice from Pruitt on a difficult situation, and Sullivan seeks help from Dr. Amelia Shepherd.

Andy returns to work while she and Jack fight to save people trapped in a collapsing bowling alley. Meanwhile, Ben confronts Sullivan about his drug problem; and Maya’s mother, Katherine, pays Maya a visit.

Ben, Jackson and Emmett are put in a precarious and dangerous position with a potential victim. Andy’s search for more background on her family opens her eyes, and Vic and Travis are caught in the middle of a corruption scheme.

When the COVID-19 pandemic hits Seattle, the Station 19 crew leans on each other for support. Andy tries to make sense of her mother’s return, while Sullivan settles into a new routine. And it’s all-hands-on-deck when a group of teenagers unintentionally starts a wild fire.

Ben and Dean wrestle with life and death after the Black Fighter’s Coalition banquet.

Maya addresses some unresolved family issues, and the crew takes matters into their own hands when faced with a life-or-death moment on scene. Meanwhile, Andy and Sullivan’s marriage is put to the test.

Station 19 and Station 23 each attempt to celebrate Thanksgiving following the fallout from the neighborhood explosion. The firefighters come together to cook, toast to loved ones they have lost, and celebrate the families they have become.

Vic and Jack lean on one another as they process the loss of Dean while Ben and Bailey try to convince Dean’s parents to allow them to raise Pru. Meanwhile at Station 23, Andy’s role temporarily expands and Sullivan subs in. Carina and Maya explore growing their family.

It’s the most wonderful time of the year and the firefighters have their hands full responding to a number of crises throughout Seattle. Putting aside their differences and personal drama, they come together to try and achieve a Christmas miracle.

Through a series of flashbacks, Sullivan and Natasha’s past is revealed. Meanwhile, Ben and Bailey have a discussion with Pru’s grandparents, and the crew responds to a fire at a candy factory.

Andy tracks down a witness to testify at her trial. Meanwhile, Carina and Maya deal with a stressful situation, and the crew responds to a car wreck.

A simulation fire training goes dangerously wrong. Maya tries to make amends, and Bailey encourages Carina to listen. Meanwhile, Jack’s sister shows up at the station with a friend, an injury and an attitude.

The crew finds themselves in the middle of a family dispute and a renovation that’s gone off the rails. Ben crashes as Bailey and Carina go undercover at a crisis pregnancy center. Travis preps with Eli for a mayoral town hall.

The team responds to a tragic freeway pileup. Andy helps Natasha face the fallout of a recent decision just as Ben deals with the fallout of his own.

The Station 19 crew trade in their turnouts for tuxes and gowns as they attend the Firefighters Ball, but when disaster strikes, they jump into action to save the day.

The Station 19 crew struts their stuff at the FABruary Winter Pride parade, where Maya encounters someone important from her past. Carina looks to Bailey for support, while Travis and Eli arrive at a crossroads.

The crew responds to a call at a local park, only to have their assumptions challenged by the Tulalip Tribe when they arrive. Meanwhile, Maya confronts her past, and Carina goes on the offense.

As Station 19 continues to battle an existential wildfire, the team grapples with the possibility of a future that will be changed forever.