After returning from Alcatraz, Bumpy Johnson seeks to regain control of Harlem. With the streets controlled by the Italian mob, Bumpy must take on the Genovese crime family, led by Vincent “Chin” Gigante.

Cassius Clay battles local boxing hero Doug Jones in the ring. Mayme insists Bumpy back Jones, an advocate for her Harlem Youth organization, but Malcolm urges Bumpy to back Clay. Meanwhile, Chin engages in a turf war for Harlem with Bonnano.

Jose Battle asks for a favor from his new partner Bumpy Johnson: a political assassination. Malcolm X is detained by Saudi authorities when he travels to Mecca. The district attorney's office targets Mayme for her gangster ties.