Larry and Jane seek new purpose in Keeg and Kay’s absence. Vic attempts to reconnect with his old crew. A mysterious invitation to a retrospective comes at the perfect time for a newly ousted Rita.

When Rita awakens unexpectedly aged, a mishandled spell teenage-ifies the Doom Patrol just as Willoughby asks for their help stopping the rise of Immortus and the end of the world as they know it.

With the end of existence imminent, a determined Doom Patrol seek to get their longevities back and save the universe.

As Jane ropes Cliff into longevity-hunting, Vic and Deric search for Larry, and Rouge tries to sway Rita into joining her on a trip to Orqwith.

As Dorothy and Casey team up for a new mission, the Doom Patrol's pursuit of Immortus leads them to a superhero parade.

Thrown into a time stream, the Doom Patrol have just one hour to find their longevities, rescue Rita, and save the world.

After returning to Cloverton, the Doom Patrol gather for a final mission one that proves to be unlike any they've had before.