The passengers from Flight 828 find themselves under government scrutiny as they struggle to resume their lives. Michaela is forced to confront the fact that Jared is married to her once-best friend, while Ben tries to help a fellow passenger reconnect with his son. Cal is approached by an obsessive stranger, as Grace and Olive disagree on whether or not to reveal a devastating secret.

Michaela and Saanvi have a similar vision, but it takes them some trial, error and teamwork to heed the call; Jared takes the fall for Michaela's misstep at work; Ben comes face-to-face with the man who replaced him.

Flashbacks reveal how Grace, Olive and Jared coped with the loss of their loved ones after the disappearance of Flight 828; Ben tries to escape the voice in his mind by going on an adventure with Cal; Michaela struggles with her feelings for Jared.

When Cal wakes with a life-threatening fever, Grace worries it's a side-effect of his experimental cancer treatment, but Michaela and Ben suspect Cal's condition may be related to a mysterious passenger from Flight 828. As Cal's situation worsens, Ben and Michaela attempt to track down the now-missing passenger.

With the detained passengers secretly moved and subjected to painful experimentation - and Cal's health directly linked to them - Ben takes advantage of an old friend to find out where the passengers were taken. Meanwhile, a mysterious new version of the calling pulls Michaela into a murder investigation that has deep personal ramifications for her.

Michaela's mystifying, next-level calling launches her on a mission that brings her relationship with Jared to a head. Determined to protect his family, Ben explores an alternate meaning to Michaela's calling that leads him to a new alliance and a powerful new adversary. Cal's struggle with Ben's absence from home forces the Stones into an agonizing confrontation that could alter the family's fabric forever.

A threat to the Stone family tests Michaela’s commitment to play by the rules and forces Grace to make a difficult decision. Ben enlists the aid of an old rival to save an old friend. Olive helps a new friend solve a calling that unearths a startling connection.

While in pursuit of criminals, Michaela is sidelined by devastating news. Ben teams up with a gifted 828er to aid a young teen. As Grace confronts ancient family wounds, Olive explores ancient mythology in hopes of helping all the passengers.

Michaela’s premonition leads her to pursue a fugitive. Ben tries to gain the trust of an unlikely ally. Olive’s relationship with Levi leads to a fascinating discovery. Jared and Drea uncover devastating secrets. Saanvi finds herself faced with a dilemma that may jeopardize the Eureka project.