When a prison bus crashes, all units must respond as some inmates face severe injuries while others seek an opportunity to flee. In the wake of the accident, Officer Nolan tries to impress an FBI hostage negotiator while tracking down an escaped convict.

A massive earthquake rocks the city and throws everyone’s patrols and its citizens into chaos. Meanwhile, agent Russo recommends Officer Nolan for a protective detail of Brad Hayes, a man whose dealings have put a target on his head.

As the rookies prepare for a big exam to see who moves on to the next stage of training, Officer Nolan and Officer Bishop are called to the scene of a murder and learn that the victim may be tied to a potential terrorist attack on the city of Los Angeles.

Danger is ever-present as the officers of the Mid-Wilshire precinct grapple with the aftermath of a plotted attack on the city of Los Angeles, leaving Officer Bradford fighting for his life.

Officer Nolan navigates building tension in his relationship with Jessica and a developing rapport with Grace while working a high-stakes criminal case involving an undercover homeland security agent. Meanwhile, Officer Chen meddles with Officer Bradford’s love life, and Officer Lopez learns some surprising news about Wesley.

An emergency alert of an impending missile attack sends Los Angeles into chaos and uncertainty, while the officers each try to keep the peace and deal with their own disasters.

John and Jessica’s relationship gets a lot more complicated after she delivers some surprising news. Meanwhile, Officer Bradford and Office West are assigned a community policing project helping out the Watts Rams as volunteer coaches at their fall clinic, along with Rams players Eric Weddle and Robert Woods.