Reynolds begins to build his department as Dr. Sharpe battles skepticism from a patient's parents. Meanwhile, Max helps Bloom find a solution for a pregnant patient in a tough spot, all the while continuing to avoid the reality of his diagnosis.

As the doctors continue to weather the storm without power, Max relies on an unlikely source to get the lights back on. Reynolds must get creative as he continues to work to save Hugh with very few resources.

When Kapoor introduces a patient to Iggy's PTSD group, a creative treatment plan causes turmoil. Sharpe discovers a long-kept secret regarding a patient.

When tasked with turning the opioid epidemic around, Max shuts down the ED and proposes a massive change. Meanwhile, Sharpe goes great lengths to prove a point.

Max resists an idea that could bring New Amsterdam more revenue. Iggy pushes back on the new telemedicine system. Sharpe uncovers a startling trend while treating a beloved former patient.

Sharpe offers help to a reluctant Mina. Max is faced with a tough decision about Luna. Bloom and Casey treat a patient who has been hiding a lifelong secret. Iggy finds himself in a very dangerous predicament. Reynolds treats a young heart transplant patient with astonishing symptoms.

Max and Bloom are shocked when a deadly ambulance crash reveals a dangerous plan. Dr. Fuentes pressures Iggy to take on patients. Sharpe realizes her own cost-cutting has adversely affected her department. Reynolds, Baptiste and Malvo strive to reach an accord.

Max discovers a fatal flaw in Dr. Fuentes' scheme to purchase the UMI medical clinic, which could be her ultimate undoing. Bloom treats two high school students for life-threatening injuries and uncovers a dangerous situation. Reynolds helps a brother and sister confront a family crisis.