Dr. Max Goodwin shakes up the status quo on his first day as medical director of New Amsterdam, the oldest public hospital in the United States, while simultaneously dealing with his own personal and health issues.

When a NYPD officer is hit by a car in the line of duty, the hospital is turn upside down trying to save her. Meanwhile, Kapoor and Iggy work with a patient struggling with a previous surgery.

When Sharpe has a case that hits close to home, she and Max team up to make things right for the patient. Meanwhile, Iggy and Bloom are forced to make a tough call on a unique situation.