Max struggles with a new fiscal reality at the hospital. Dr. Sharpe is on a mission to provide follow-up cancer screenings for patients before it’s too late. Bloom grapples with Dr. Shinwari’s new overnight schedule. Reynolds has an interesting conversation with Dr. Malvo about their future.

The New Amsterdam team goes out for a night of karaoke and drinking, but must face the consequences at work the next day. Iggy helps a mysterious patient confront a past trauma. Reynolds and Dr Malvo discuss their future. Leyla gives Lauren some bad news.

An explosion at a wedding ceremony sends a stream of injured partygoers into New Amsterdam. While Max and Dr. Wilder scramble to find a rare blood type to save the groom, Reynolds and Bloom treat a couple with bizarre injuries. While helping a young girl out of a catatonic state, Iggy learns the truth about the wedding.