The Turtles discover for the first time that they are not the weirdest things in New York when they encounter two villains from the Hidden City pursing a cat-like agent. They have their first encounter with Baron Draxum who is making mutants with the help of his Oozesquitos.

In order to save April's job as a party captain at Albearto's Pizzeria, Donnie upgrades the main animatronic of Albearto, only for it to go out of control.

While looking for gifts for Splinter, the Turtles traverse through Times Square where they fight the thuggish mascots lurking there.

Hypno-Potamus returns and causes havoc at April's homecoming dance by hypnotizing the attendees.

The Turtles look for a way to eliminate New York City's Oozesquito problem.