Jack faces off with Gideon Graham, a famous professor and philosopher who slipped into a responsive catatonic state following a lightning strike that killed his wife. To help Gideon, Jack tries an unusual treatment that may pose a risk to his patient. Meanwhile, Jack finds himself attracted to the patient's daughter.

An 8-year-old bipolar boy is admitted to Wharton Memorial following a dangerous incident with a knife. When Jack uncovers the accident was a suicide attempt, Jack tries to get inside the boy's head to learn what is causing his outbursts. Meanwhile, Nora learns her daughter is posting provocative pictures of herself on the Internet.

Jack attempts to talk down Leonard Steinberg, a gambling addict seriously in debt, threatens to jump off the roof of Wharton Memorial. Later, Jack heads to court in order to testify on behalf of a mentally incapable patient who is charged with manslaughter by a high-profile attorney who has never lost a case, Marcie Crane. Jack's expertise will be tested when the case turns out to be much more complicated than originally thought. Meanwhile, Jack and the team show up for a poker game after work, where sparks fly between Rylan and Veronica.

An accident on the job has caused a construction worker to have physiological and psychological problems for Jack to treat. The incident details don't match what was written in the report, but instead match up with a more serious accident which occurred 100 years earlier.

A factory worker has a few fingers chopped off yet refuses to have surgery to reattach them. Meanwhile, Jack argues with his colleagues over Veronica being assigned his sister Becky's case of schizophrenia.