Following an emotional breakup, tough but tender FBI super-agent Will Chase (code name: "Whiskey Cavalier") is assigned to work with badass CIA operative Frankie Trowbridge (code name: "Fiery Tribune"). Together, they must lead an inter-agency team of flawed, funny and heroic spies who periodically save the world - and each other - while navigating the rocky roads of friendship, romance and office politics.

The team heads to Europe to transport a dangerous prisoner for interrogation, and the prisoner is Will's former boss; Jai helps organize a Secret Santa gift exchange for an off-season Spy Christmas.

Will goes to a dark place as he and the rest of the team are tasked with hunting down the culprit behind an unsettling attack.

Ollerman attempts to force the team to commit a terrorist attack for The Trust using Ray’s life as leverage. Meanwhile, Jai helps Standish deal with a revelation about Tina, and Will and Frankie come to a realization about their relationship.