Romano, Pencil and the Pope dominate Amsterdam's busy cocaine trade. When Pope betrays Romano and Pencil a vengeful war is set off between them. Away from the street, a seasoned journalist and his naive apprentice sense a headline story in the making.

Romano seeks legal council to secure his personal future, and that of his empire. The Pope feels the pressure and Is ready to retaliate, while Matthijs sets out to prove himself to Rein with a headline story.

The Pope's ruthless actions push several characters to the edge of their sanity. Meanwhile, Adil attempts to deal with the cash flow of the inherited empire and Rein struggles to cope with his loss.

An unexpected turn betrayal endangers the lives of both Rein and Mo, while Mouse and Adil plot to take action before more suffer at the hands of The Pope. In prison, Romano's circumstances change radically.

Van Jaren competes with both Taxi and Samira. Adil has nowhere to go and goes looking for Meltem. Paus makes new enemies and makes an irreversible decision.