High school sweethearts Maria and Garret land jobs at a local hospital as nursing assistants. Three days in the paranormal activity begins. What's at first a novelty escalates to a final confrontation when a demonic entity follows them home. When nurse Eileen visits her aunt in hospital, she is confronted by a terrifying reality, her aunt is sicker than the doctor's let on. But nothing prepares her for what she sees next, an evil creature hovering over her aunt's bed. A husband and wife visit their grandma in her nursing home and stay overnight in one of the facility's guest rooms. Overcome by the smell of decomposition in the middle of the night, the couple soon finds the odors source - a frightening ghost bent on terror.

Lab technician Jessica, working the night shift in the creepy basement of a hospital, is stalked by otherworldly spirits. Locked doors burst open, while others refuse to come unlocked and hundred pound objects are tossed across the room. Things come to a boil when the spirit manifests in the back of her car and offers a dire warning. Hospital volunteer Bettina has a spectacular gift -- she can heal the sick. It's a gift she must use sparingly because healing the sick dwindles her health. Using her gift to rescue a coma patient attracts the attention of a dark entity eager to drain her power and increase his own. A paranormal radio show host wasn't expecting to have to have emergency surgery. The unexpected escalates when he wakes up in a recovery room populated by angry and aggravated spirits.

A new nurse's life is spared when ghost doctor warns her about a violent patient. After surviving the encounter, Nurse Phyllis must fight for another patient's soul after she's possessed by a powerful evil presence. Hospice nurse Suzanne denies the existence of the paranormal even after a co-worker admits to seeing spirits in their workplace. Then she finds herself in a tense stand-off with a patient's ghost as she preps his body for the morgue, forcing her to confront not just the spirit but her disbelief. A man takes a demanding job as a cook in a hospital with a disturbing history. Repeated paranormal encounters with ghostly shadow creatures make him so emotionally and physically drained, he makes a life-changing decision.