High school sweethearts Maria and Garret land jobs at a local hospital as nursing assistants. Three days in the paranormal activity begins. What's at first a novelty escalates to a final confrontation when a demonic entity follows them home. When nurse Eileen visits her aunt in hospital, she is confronted by a terrifying reality, her aunt is sicker than the doctor's let on. But nothing prepares her for what she sees next, an evil creature hovering over her aunt's bed. A husband and wife visit their grandma in her nursing home and stay overnight in one of the facility's guest rooms. Overcome by the smell of decomposition in the middle of the night, the couple soon finds the odors source - a frightening ghost bent on terror.

Moving objects, lockers doors that shut themselves, staff stalked by an uncanny presence -- something is haunting the 3rd floor of the hospital. As the paranormal incidents escalate, a senior nurse steels her courage as she sets out to face down the unearthly apparition. A director of nursing at a long term care facility witnesses a paraplegic suddenly regain the ability to walk. She soon realizes that what at first appeared miraculous is actually demonic possession. Nicole has a near-death experience when she's admitted to hospital for severe kidney stones. She wakes up with the ability to see a frightening ghost who manifests his eerie presence by manipulating electricity.

Lab technician Jessica, working the night shift in the creepy basement of a hospital, is stalked by otherworldly spirits. Locked doors burst open, while others refuse to come unlocked and hundred pound objects are tossed across the room. Things come to a boil when the spirit manifests in the back of her car and offers a dire warning. Hospital volunteer Bettina has a spectacular gift -- she can heal the sick. It's a gift she must use sparingly because healing the sick dwindles her health. Using her gift to rescue a coma patient attracts the attention of a dark entity eager to drain her power and increase his own. A paranormal radio show host wasn't expecting to have to have emergency surgery. The unexpected escalates when he wakes up in a recovery room populated by angry and aggravated spirits.