Yorick, Agent 355 and Dr. Mann hit a snag on their way to San Francisco. As the search for 355 heats up, Jennifer clashes with former cabinet secretary Regina Oliver, who has her eyes on the presidency. Hero is seduced by a charismatic leader, Roxanne, as Sam and Nora grapple with their place in a dangerous group of survivors.

Kimberly uncovers a secret. 355 and Allison reach an understanding. Yorick stumbles upon a mysterious town where things are not what they seem.