Hotel Del Luna disappears overnight. Chan Seong begins to trace Man Weol. The hotel staffers are having difficulty in dealing with all the work without Chan Seong. Meanwhile, Hyun Joong and Yu Na meet a group of spirits in the mountains on their way to the new hotel.

Man Weol and Chan Seong start to date without telling anyone in the hotel. A lunar eclipse occurs in 39 years, and humans get to see the presence of Hotel Del Luna. To greet special guests visiting on the day of the lunar eclipse, Chan Seong opens the door of Room 404. Meanwhile, Seol Ji Won, the serial killer, looks for Yu Na.