The Edo period. Daughter of a martial arts dojo, Rin embarks on a journey to take revenge for her slain parents. For her bodyguard on the journey, she has chosen the immortal man Manji, nicknamed the Slayer of Hundreds. Her target is the head of the Ittou-ryu, Kagehisa Anotsu, the man she hates. The adventure of the man who never dies and the girl who's sworn to live for revenge unfolds.

Discussions of the task of naming the instructor at the Ittou-ryu school, allotted them by the shogunate, have begun. They will make the Ittou-ryu's sword known to the world. Taito Magatsu vows to make that a reality, but decides to leave from Kagehisa Anotsu's side. At the same time, Ittou-ryu leaders start to be targeted. The tip of that blade is also pointed at Magatsu.

Arashino, Hasshuu, and Murasaki of the Rokki-dan act as the vanguard in the clash with the Ittou-ryu. The crucial Abayama manages to escape with the help of his followers. But then he hast to confront Giichi and Hyakurin, who pursued Abayama to assist Habaki.