A local FBI case involving two murdered women and a sea of powerful men turns into a manhunt for the dangerous leader of a far-reaching criminal enterprise.

The crossover starts on FBI S04E01 All That Glitters (I). It continues on FBI: International S01E01 Pilot (III).

New Fugitive Task Force member Kristin Gaines joins Jess and the team, as they head to D.C. to find a dangerous fugitive from the Jan. 6 Capitol riot

When a judge known for serving harsh sentences to juveniles is murdered, the team looks into his lengthy list of cases in the hunt for his killer. Also, Kristin faces family hurdles while resettling with her teenage daughter in New York City.

The team must determine if the kidnapping of a young Chinese-American woman is a random hate crime or if she was specifically targeted, in order to find her. Also, Jess and Sarah struggle with Tali’s continued rebellious streak.

After a deadly fire at an arcade, the team discovers the blaze was just the first step in an intricate plan to exact revenge on one of the victims. Also, Hana rejoins the team, finding new adjustments in all aspects of her life.

The team attempts to hunt down a family annihilator before he continues his murder spree. Also, Barnes’ intrusive mother puts pressure on her marriage.

The team investigates the murder of a professional basketball player’s wife, who was a famous lifestyle guru. Also, Kristin and her ex-husband grow closer, and Special Agent in Charge Isobel Castille checks in with the team on the high-profile case.

After a prized Kentucky racehorse is stolen and its groomer is taken hostage, the team quickly learns they may be the only ones who consider the young woman’s safety a priority over the horse’s. Also, Byron returns to celebrate the holidays with Jess and his family.

While holiday shopping, Barnes and Jess are caught in the middle of a mall shooting, with the exits rigged so no one can escape. Also, Gaines, Hana and Ortiz try to help from the outside, knowing their team's family members are inside and at risk.

The team hunts for a young man who is using napalm-style bombs to attack his targets. Also, with Tali away, Jess and Sarah begin to adjust to their empty nest.

The Fugitive Task Force chases a killer who plays a twisted game of cat and mouse with his victims. Also, Hana shares something personal about herself with her new roommate, Ortiz.

The team searches for a notorious Colombian drug lord after he escapes from a U.S. prison. Also, Kristin begins to open up to her ex-husband about her past.

The team searches for a businessman wanted for murder and an embezzlement scheme. Also, Jess takes advantage of his empty nest to properly court Sarah.

The team pursues an abusive man on the war path to find his ex-girlfriend, who is trying to escape him for good. Also, Jess and Sarah make plans to take their dream vacation together.

The team must track down a murderous member of the incel community targeting those he believes never give him a chance. Also, Barnes, Hana, Ortiz and Kristin deal with their grief in the wake of Jess’ death.

The team gets called to Vermont after a married couple who grow illegal marijuana massacres their employees. Also, Barnes begins to regret not taking any time off to bond with her new baby.

The team's new leader, charming but formidable Special Agent Remy Scott, takes charge as they investigate a series of homicides tied to a forbidden love between a young teen and her older boyfriend.

Remy and the team investigate the homicides of two Army veterans in a murder spree connected to their time in Afghanistan.

The team goes after the killer of a man in witness protection but finds there’s more to the case than meets the eye. Also, Remy is challenged by what he discovers when he reconnects with his mother, Betsy, in person.

The team searches for a murderer recreating the chilling killings of a notorious ‘80s mobster.

When a wealthy East Hamptons couple are killed by a female con artist posing as a personal trainer, the team works to find out her true identity and track her down. Also, Ortiz is put in a tough place when Hana's brother asks a favor.

The team chases an oligarch who goes on a terror spree in New York City in a desperate attempt to escape his impossible situation.

When a family of four from New York is found dead in a Georgia motel room, the Fugitive Task Force investigates a connection between the victims and the sale of illegal firearms. Also, Barnes struggles with Remy's leadership style upon her return from maternity leave, and Remy and his sister plan for their mother's care.

Rookie agent Ray Cannon joins the Fugitive Task Force as they hunt down a mysterious killer targeting IRS offices.

After a heist in the Diamond District leaves three dead, the team's search for the fugitives reveals a dangerous connection to Kristin’s undercover past in Miami.

The murder of a geology professor leads the team to uncover an ancient legend regarding a secret treasure dating to the civil war, and they encounter a deadly fugitive determined to kill to find the gold. Meanwhile, an old friend from Remy's past shakes up his relationship with April.

After Hana is kidnapped while trying to help a young girl in peril at a rest stop that's on the way to her sister's house in Connecticut, Remy and the team pull out all the stops to find her.

After a tech entrepreneur is abducted from a rave in Brooklyn and found bludgeoned to death at his estate in Connecticut, Remy and the team must dive into the world of psychedelics to find his killer.

The team's Thanksgiving plans are put on hold when they are brought in to investigate whether a shooting at a Buddhist temple was a hate crime or something more personal. Also, Remy and April make a tough decision.

When three prosecutors are assassinated outside a bar in their small Arkansas town, the team is called in to determine if this was a personal vendetta; Ray feels compelled to help a woman and her young son combat an injustice.

When a celebrity child psychiatrist is kidnapped by the relative of a former client, the team races to track down the perpetrator and learns what really happened to the psychiatrist's client; Kristin confronts her deep-rooted trauma.

The team is thrown for a loop when they discover the abductor of a disgraced state police detective is connected to someone from a recent case.

As the team chases after the suspects behind an explosion at an Ohio energy plant, they are led towards a major crypto company with enemies looking to take it down; Remy and his sister close a chapter in their lives.

When two Vermont teens are kidnapped on their way home from a basketball game, the team is led to a wayward pastor and his brother. Also, Remy attends a hearing for his brother's murderer.

The team must navigate the mistrust of authorities in a tight-knit Somali community in Minnesota as they race to find a kidnapped 14-year-old girl.

When a rising star athlete is found violently murdered, the team chases after one of her teammates and his girlfriend; Remy reunites with a true crime show producer from his past.

The Fugitive Task Force springs into action to find a famous foreign tennis player after she's kidnapped from a tennis court in Brooklyn.

The clock ticks as the FBI and FBI: Most Wanted teams join forces to hunt down the fugitive terrorists as they get closer to carrying out a plot to destroy a major New York City landmark and cause devastating civilian casualties.

The crossover starts on FBI: International S02E16 Imminent Threat (I) and FBI S05E17 Imminent Threat (II).

The team jumps into action to find two missing coeds after their roommate Carly Cassidy’s older brother is involved in a homicide that took place in their dorm room. Also, Hana becomes distracted when she meets someone online.

After two agents from the Bureau of Land Management go missing while executing a land seizure warrant in Wyoming, the Fugitive Task Force heads west to track them down in an unwelcoming county; Hana receives a threat.

When a news anchor is shot dead in the station's parking lot, the task force must dive into a story she was working on to track down her killer; Remy debates revisiting the case around his brother's murder.

The witness Remy and Kristen are visiting in prison is put in danger when a riot breaks out, leaving the staff and visitors held hostage by two murderous gangs.

The Fugitive Task Force searches for a missing migrant teen they believe was lured into unlawful work by a dangerous man. Also, Remy learns of a previously undisclosed witness in his brother’s murder case.

The team helps Remy try to catch his brother’s real killer 25 years after Mikey was murdered.