When Jinks' old pal Howard visits, the two begin having fun with Pixie and Dixie, who take it upon themselves to convince Jinks that Howard brings bad luck (since Howard is a black cat).

Jinks has inherited from Mrs. Smithers an old mansion and moves in, leaving Pixie and Dixie behind. The two mice make the place haunted to scare Jinks into going back home.

Jinks is taken to meet Master cat Gus, while Pixie and Dixie's cousin Hercules comes and unknowingly saves Jinks' bacon from Gus.

An Indian mouse named Tabu meets Pixie and Dixie and demonstrates some magic on Jinks. Tabu leaves a few magic tricks behind as he departs.

Jinks builds a robot mouse dame to get Pixie and Dixie to squabble over her affection. When they see through the trick, they use the robot mouse against Jinks.

Jinks receives a magic kit. With it, he makes Pixie and Dixie disappear. The mice aided by a bulldog to get even with him.

Jinks tries to dispose of Pixie and Dixie in a balloon. The mice are tailed by the air force and broadcast on television.

Jinks loses his job and Pixie and Dixie tries to get his job back by sending in tons of mice.

A homeward bound flea with great strength takes refuge on Jinks and prevents him from bullying Pixie and Dixie.