Three new officers in a large metropolitan police department adjust to their new jobs and way of life.

In the introductory episode of the series, the presence of several street gangs contributes to a tension-filled atmosphere. The Rookies are assigned with the challenge of maintaining order amongst the rivaling street gangs, with Willie Gillis arising as the mediator between the gangs.

Terry and Willie, while doing routine spot checks, uncover a petty thief involved in a larger fur scandal. He agrees to give information against the two criminals who orchestrated the plan. However, due to a technicality, their trial is dismissed and they set their eyes on revenge. After several attempts to drag him back into their world of crime, Webster puts an end to the two felons criminal actions.

Willie, being in the wrong place at the wrong time, is struck by a bullet in the leg by a criminal wearing a monster mask. He is left paralyzed temporarily. Further investigation reveals a criminal's passion for horror films. As the case becomes more complex, Terry and Danko track the small-time crooks down to an auction, where they foolishly try to escape the law.

Terry and Willie become involved with Brother Toby, a former drug addict now turned evangelist. They admire his mission to help other junkies become sober. He is framed by the father of one of his followers, because of the father's disagreement with Toby's religious beliefs. He is put in the situation where it appears that he violates his parole by selling drugs. Willie and Terry have the harrowing task of proving Toby innocent.

A man disguised as a police officer kidnaps the daughter of a wealthy family, the Sloans. The Police Squad are quick to react to the kidnapping. The kidnapper writes a ransom note demanding two hundred thousand dollars, Meanwhile, Danko, Webster and Gillis notice that Ryker appears to be distracted. A fainting spell places him in the hospital, where he confides in Jill that the kidnapped girl may in fact be his biological daughter.

A young woman, Andrea Sloan, is kidnapped and held for ransom. Complications ensue.

Assigned with the task of protecting a valuable witness, Danko and the Officers must exercise caution regarding visitors to the prison. When a professional killer disguises himself as a professor seeking to interview Sol (the witness), Danko denies him the opportunity. Nevertheless, Danko does agree to help the 'professor' by accompanying him to an aircraft hanger where he claims he is meeting a friend.

Assigned with the task of protecting a valuable witness, Danko and the Officers must exercise caution regarding visitors to the prison. When a professional killer disguises himself as a professor seeking to interview Sol (the witness), Danko denies him the opportunity. Nevertheless, Danko does agree to help the 'professor' by accompanying him to an aircraft hanger where he claims he is meeting a friend.

After three woman are murdered, the Police Squad takes action. In order to solve the mysterious murders and prevent future ones, the Squad welcomes two women officers to the force, Dawson and Conway. A plan is created which places Dawson and Conway in an apartment complex together, with Webster and Gillis across the hall.

In an effort to prove he's no 'old man', Officer Danko chases down a fleeing criminal. While he succeeds in apprehending the thief, his partners Webster and Gillis fail to catch the criminal's brother, who is also running from the law. Danko testifies in court against the criminal he caught, thereby infuriating the brother who is unassumingly observing in the courtroom.

The rookies are given the task of protecting a controversial Army General who has recently returned to the country after serving in Vietnam. The rookies must deal with mob control, as well as actively track down a sniper who hits the General. The rookies most valuable clue is an old army rifle, used in the General's shooting, whose owner the rookies must uncover.

Easy Wyatt is a cop with many years behind him on the force. His ranch has recently been the target of destruction in a new plan to build a freeway. Wyatt is becoming mentally unstable, and his instability is slowly spiraling deeper and deeper. Once the best officer in the squad, Wyatt's shaky state is evident when he attempts to prevent the bulldozers from digging by holding them at gunpoint.

The rookies are on the hunt for a runaway girl. Their strongest clue to solving the case is a tattooed foot. However, the rookies are missing a vital piece of information: the man that claims to be the girl's father is actually the one who is out to murder her, and is the cause for her self-imposed disappearance.

Gillis enters a tough situation when he is presented with a boy who is trapped in a police car which is on fire. He chooses to shoot the boy, promptly catching the internal affairs division's attention. They launch an investigation into the event and Gillis to see if he has committed a mercy killing, and to try to get closure in the case.

In their off duty time, the rookies become involved in a camp for deviant, delinquent children and adolescents. Because of their involvement, the community's view regarding them, and the police force as a whole, is at risk.

A junkie addicted to dope sets his eye on swiping 82 million dollars worth of cocaine which has been confiscated. He will soon find that his plan is confronted with complications: the police have tagged the drugs for disposal in the ocean.

An old friend of Terry Webster's unleashes an attack on a patrol car officer. Webster investigates further to try and discover the logic behind the seemingly nonsensical incident.

A daring plan is crafted by a convict's wife to release a prisoner from incarceration: an innocent and helpless police officer, who is undergoing surgery, is taken hostage. The rest of the medical staff in the operating room is also put at risk, including Jill Danko, Mike Danko's wife.

An extremely ill young boy is desperately waiting for a suitable bone marrow donor; without a bone marrow transplant, he will die shortly. However, the biggest obstacle is that the boy's father, who has compatible marrow and is the only possible donor, is currently on the run. He is trying to evade the police as well as the syndicate.

The rookies try to disengage a robbery network by leaving the undesirable city slums and working in the suburbs. They discover that the main suspect is a dear, old friend of Lieutenant Ryker's. The man is also a special security guard of the community.

The rookies are presented with a ""difficult"" court case. While the case is essentially an open and shut, obvious manslaughter conviction, trouble arises: the most important element in the conviction, the only witness, is discovered to suffer from mental retardation.

The rookies may be confronted with a problem worse than the nurse who holds a grudge against all police officers: they discover that her younger brother is associating with thugs who are the organizers of a current neighborhood protection scandal.

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Willie and Terry are kidnapped by a disturbed criminal who is dying. The criminal leaves the two rookies in the desert, abandoned, with no food source and little hope of being rescued. Willie, in this situation, struggles to saves Terry's life.

While performing their routine patrol, Gillis and Danko unexpectedly stumble upon a robbery that is taking place. They radio for additional support and a veteran police team arrive at the crime scene. One of the veteran policeman is killed in the midst of the robbery, and his partner places fault on Danko. The veteran policeman makes the suggestion that Danko be appointed to ride with him, a suggestion that turns out to have almost catastrophic results.

Webster is asked to play the role of a prisoner at the State Prison. He disguises himself as an inmate, in an effort to aid the issue of prison reform. However, when the other prisoners discover that Webster is merely pretending to be a fellow inmate, pandemonium results.

Juvenile detail is typically known to be a relatively easy tour. However, this is not the case for Willie. While on juvenile detail, Willie discovers that he is not as emotionally strong as he once thought. He is presented with pain and death, in amounts that are greater than he can manage.

Jill, Danko's wife, is assigned to protect Lieutenant Ryker after he is wounded by a former prisoner who desires to take revenge. However, Ryker decides to take charge of the situation when Jill's life is at stake.

A lonely lady who resides by the beach places a call into the police station for aid. Willie and Terry ignore this routine call, only to find out that the call was legitimate and the woman has been robbed and beaten. The rookies are then thrown into a peculiar series of robberies.

Jill Danko is seriously wounded by a seemingly demented gunman while dining with her husband Mike. Later, they find out that the gunman is unable to be prosecuted in court, because he is suffering from a brain tumor which appears to be the cause of his action. The rookies take it upon themselves to prove the man is dangerous and can place society in jeopardy.

Like many Vietnam veterans returning home after the war, Jimmy Webster is angry at society for treating him as if he was an outsider, and not openly accepting him. He is unable to find employment and is left with an important decision to make: either he can fall back on his cousin, Terry Webster, and turn to him for support, or he can join a robbery operation and make a large amount of money.

A young nurse suffers a terrifying ordeal when she is raped in the underground garage of Memorial Hospital. The rookies attempt to help the woman by offering support. They offer encouragement and assistance as the woman proceeds through the legal formalities which often are unsympathetic to the rape victim, and sometimes humiliate her.

Lieutenant Ryker is selected to be personally in charge of an important investigation. A priest is murdered and a nun is badly beaten in a destitute neighborhood, and the community worries that religious restlessness with arise. As the investigation progresses, the rookies uncover a completely different motive.

A telethon featuring an extremely famous country western singer requests of the police department extra protection. The rookies are assigned to the event. Their placement on this assignment results in their protecting the singer from a couple of bitter and unforgiving country folk from Tennessee. The hillbillies hold the singer responsible for the death of their sister, who died while she was giving birth.

Jill is confronted by her past when a former lover of hers appears at her home. Mike is currently out of town. The unanticipated visitor gives the impression that he is fatally ill, thereby luring Jill into becoming involved with him, despite her uncertainty. Only after a period of time does Jill realize the great lengths this former lover will go to try to get her back and claim her as his own.

A retired police lieutenant interferes in the investigation of an aggravated assault involving his best friend.

One of Willie's young female friends is desperately afraid when she discovers that she is afflicted with diabetes. After she makes the realization, the young woman flees to a drug rehabilitation center, to be around the other young people whom she trusts. However, she neglects to bring her insulin.

Willie Gillis is assigned to ride with an older officer and, while on patrol, the man is killed. When the murderer is captured, the other policemen are inclined to take the law into their own hands. Falsely accused of incompetence, Willie is forced to search his soul to arrive at justice.

A college girl from Jamaica witnesses the murder of a notorious drug pusher and Terry Webster is assigned to get her testimony in the days that follow, they fall in love, but the girl is tracked down by the murderer and killed. Terry uses himself as a decoy to trap the killers.

Mike and Jill Danko's marriage is strained by Mike's protective interest in the widow of a man Mike was forced to kill in the line of duty.

The rookies must contend with 'The Teacher' an ex-convict who masterminds several well executed robberies using the young boys who are in the city looking for excitement.

A young man with a Jekyll - Hyde personality becomes a puzzle for Terry and Willie when he gives them a description of a suspected cop-killer. But for Mike and Ryker he poses a different problem: extreme danger.

An old friend of Ryker's, once a good policeman and now a pathetic drunk, is framed for the murder of a gangster who has terrorized the neighborhood. To gain favor from his daughter and neighbors, he pleads guilty, but Lt. Ryker, with the help of the rookies, finds a better way to give the man back his dignity.

The Ludlow precinct institutes a Police Cadet Program. One of the boys involved becomes overzealous and is kidnapped, along with Terry, by his sister's boyfriend who is a fugitive.

A brilliant young felon holds Terry and three women, one of whom is pregnant, hostage in a bank vault in order to free his partner from jail.

Two ex-convicts are loose in the city carrying contagious meningitis. After Willie is exposed to it when he gives the ex-convict mouth - to – mouth resuscitation, the other rookies are given the task of finding the men and stopping a possible epidemic.