Set in the fictional town of Kamurocho, the story unfolds across two intersecting timelines—1995 and 2005. In 1995, four friends eager to escape their restrictive lives in an orphanage dive into the yakuza-controlled underworld of 1995 Kamurocho. Meanwhile, in 2005, their friendship is deteriorated, as tensions between the Tojo Clan and the Omi Alliance are at a boiling point.

Set in a small restaurant in the corner of a shopping district. The unusual eatery is only open after midnight, and its standard menu consists of just a single choice. However, the customers still come for the amusing chatter and the proprietor's willingness to cook any dish that they request. This drama depicts the lives of the restaurant's patrons, including a yakuza, an unsuccessful actor, a group of office ladies, a newspaper delivery boy, and a stripper.

To deal with the increasing violent crime rate in the Shinjuku area of Tokyo, a special investigation team is formed at the Shinjuku Police Station. Detective Shunsuke Yamashita and Detective Keiichi Tashiro begin work at the special investigation team. Detective Shunsuke Yamashita doesn't care about details and says what he thinks. Meanwhile, Detective Keiichi Tashiro is diligent and enthusiastic with his investigative work. The two men frequently argue, but also cooperate to solve the cases.