Selepas malapetaka virus, kemerdekaan Jepun dirampas GHQ. Apabila seorang pelajar sekolah tinggi, Shu, memperoleh kuasa aneh, dia tertarik untuk menyertai pemberontakan.

In the near future, Doc Terror and his cyborg companion Hacker unleash their forces to conquer Earth! Only one force can stop this evil: a handful of brave men. In specially created Exo-Frames, they can be transported anywhere to fuse with incredible assault weapon systems beamed down from the space station Skyvault, becoming man and machine, Power Xtreme! Max Ray, brilliant Sea Operations commander! Jake Rockwell, rugged Land Operations specialist! Ace McCloud, daring Air Operations expert! Whatever the challenge, they are ready - The Centurions!

In the continent of Cruzon, an impending war between the Kingdom of Krisna and the nation of Athens is brimming. The people of this land are able to use quartz for whatever purpose they desire. Yet one person, Rygart Arrow, is not. He is an "un-sorcerer," a person unable to use quartz. But this characteristic will enable him to pilot an ancient Golem, one strong enough to put up a fight against the invading army of Athens.

All hell literally breaks loose on the day that Millennium Demon King gets "resurrected" accidentally by the God of Light. The unfortunate event leads to countless junior demons rising into the fairy world, threatening to destroy the beauty and wonders of many fantasies. In a desperate attempt to rescue the fairy world from the demonic influence and invasion, the Light of God seeks the help of the 12 Zodiac Warriors to protect and preserve its peace.