Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.

The life of internationally renowned artist and activist Nan Goldin is told through her slideshows, intimate interviews, ground-breaking photography, and rare footage of her personal fight to hold the Sackler family accountable for the overdose crisis.

Americans consume 75% of the world’s prescription drugs. After losing his own brother to the growing epidemic of prescription drug abuse, documentarian Chris Bell sets out to demystify this insidious addiction. Bell’s examination into the motives of big pharma and doctors in this ever-growing market leads him to meet with experts on the nature of addiction, survivors with first-hand accounts of their struggle, and whistleblowers who testify to the dollar-driven aims of pharmaceutical corporations. Ultimately his investigation will point back to where it all began: his own front door.

Artistic lovers, Viv and Jay, have become trapped in a vicious cycle of codependent heroin addiction. But when Viv’s wealthy parents hire an interventionist to take Viv to rehab, the couple decides to set off on their own with the help of a suboxone prescription... all they have to do is survive a harrowing night through drug withdrawal.

American Pain tells the jaw-dropping story of twin brothers Chris and Jeff George who open up a chain of pain clinics in Florida where they hand out pain pills like candy.

A family affected by the opioid crisis struggles to stay together.