苏凯（郭涛 饰）是一个专门替人从外地运送汽车的个体司机，偶然机会，他邂逅了空姐林格格（徐帆 饰），并对其一见钟情。然而苏凯表面贫嘴油滑的样子未给林留下好的印象，经过一番周折，林渐渐对苏产生好感，两人陷入热恋之中。苏凯用卖旧房得来的钱在公路旁买地建房，准备营建温馨的二人世界。但一场灾难不期而至，苏凯被诊断患有一种名为“肌无力性疾病”的绝症，命不久矣。为了不拖累爱人，他隐瞒了自己的病情，并将林赶了出去。林的好友杨艳（剧雪 饰）得知真相后，选择照顾苏凯的起居。经过一段时间的相处，杨艳也开始喜欢上这个生命将逝的男人……

Su Kai is spunky but lonesome: his job takes him on long solitary drives across China. On a ferry, he meets two China Air flight attendants, Ge Ge and Yang Yan. He's smitten by Ge Ge, and within a few days, she agrees to move in with him. They borrow money, build a house, live in harmony, and plan a wedding. Then, a sudden turn of events brings a change in Su Kai; he becomes moody and remote. Is there any way Ge Ge can salvage their relationship? Su Kai's breakdown brings Yang Yan back into the picture as well, and her feelings become central to the story.