Susannah Walker Wise is an English television and stage actress.

She trained as an actress at the London Academy of Music and Dramatic Art, graduating in 1995. Wise is best known for her work in the soap opera EastEnders and the Channel 4 comedy Peep Show. On stage, she has had roles in Christopher Shinn's Where Do We Live and in Nina Raine's Rabbit. She also played Rebecca Shaw in the Channel 4 series Derek. She appeared in the final episode of Kavanagh QC, starring John Thaw, in 2001. In 2015 she portrayed Sylvie in the Mystery miniseries The Enfield Haunting. In 2020 she appeared as Emily Helmsley in Father Brown episode 8.10 "The Tower of Lost Souls".

Her debut novel This Fragile Earth was released in 2021, her second novel Okay Then That’s Great in 2022. Both books have been longlisted for the Mslexia prize