Danny Thomas, nascut Amos Alphonsus Muzyad Yaqoob (Deerfield, Míchigan, 6 de gener de 1912 - Los Angeles, Califòrnia, 6 de febrer de 1991) va ser un actor, cantant, humorista i productor nord-americà d'ascendència libanesa.

Danny Thomas (born Amos Muzyad Yakhoob Kairouz; January 6, 1912 – February 6, 1991) was an American nightclub comedian and television and film actor and producer, whose career spanned five decades. Thomas was best known for starring in the television sitcom Make Room for Daddy (also known as The Danny Thomas Show). He was also the founder of St. Jude Children's Research Hospital. He is the father of Marlo Thomas, Terre Thomas, and Tony Thomas