Rosalie Anderson MacDowell (born April 21, 1958) is an American actress and former fashion model. MacDowell's known for her starring film roles in romantic comedies and dramas. MacDowell has modeled for Calvin Klein and has been a spokeswoman for L'Oréal since 1986.

Her early films include Greystoke: The Legend of Tarzan, Lord of the Apes (1984) and the Brat Pack vehicle film St. Elmo's Fire (1985). Her breakout role was in Sex, Lies, and Videotape (1989) which earned her the Independent Spirit Award for Best Female Lead and a nomination for a Golden Globe Award for Best Actress – Motion Picture Drama. She then starred in a series of films including Green Card (1990), Groundhog Day (1993), Short Cuts (1993), Four Weddings and a Funeral (1994), Michael (1996), Multiplicity (1996), and The Muse (1999).

She's also known for her supporting film roles in Beauty Shop (2005), Footloose (2011), Magic Mike XXL (2015), Love After Love (2017), and Ready or Not (2019). She co-starred and opposite her daughter Margaret Qualley in the Netflix miniseries Maid (2021) for which she was nominated for a Golden Globe Award for Best Supporting Actress – Series, Miniseries or Television Film.