Jeffrey D. Nathanson is an American filmmaker.

Nathanson was born in Los Angeles County, California. He attended the University of California, Santa Barbara, as an English major from 1983 to 1985. While at UC Santa Barbara, he worked on the school's newspaper, the Daily Nexus, and has stated that the courses he took at UC Santa Barbara led him to want to become a screenwriter. He later enrolled in the screenwriting program at the AFI Conservatory for one year.

He is best known for his work on the Rush Hour sequels, Rush Hour 2 and Rush Hour 3; Catch Me If You Can; The Terminal; and The Last Shot. He co-wrote a story draft for the film Indiana Jones and the Kingdom of the Crystal Skull (2008) with George Lucas; the film was directed by Steven Spielberg. He wrote the screenplay for Pirates of the Caribbean: Dead Men Tell No Tales (2017), on which he also received a story by co-credit, the latter with Terry Rossio. He wrote the script for the 2019 live-action remake of The Lion King for Disney, directed by Jon Favreau. He has also been announced to write its upcoming prequel, Mufasa: The Lion King, directed instead by Barry Jenkins.

On October 3, 2017, it was reported that Nathanson would be penning a script for a biographical film directed by Brett Ratner based on the life of the Playboy founder Hugh Hefner, who will be portrayed by Academy Award winner Jared Leto, but the biopic was put indefinitely on hold, and it was confirmed that Leto would not portray the Playboy founder following an emergence of sexual harassment allegations against Ratner on November 2, 2017. 

Nathanson was nominated for a Best Original Screenplay British Academy of Film and Television Arts Award for his work on Catch Me If You Can.

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