Samantha Smith is known for her role as Mary Winchester on the TV supernatural show "Supernatural (The WB: 2005-2006, The CW: 2006-)".

Some other TV shows she appeared on are "Seinfeld", "Wings", "The Pretender", "Silk Stalkings", "Pacific Blue", "Caroline in the City", "Buddy Faro", "Cold Feet", "Friends", 'Two of a Kind", "Family Law", "Time of Your Life", "Profiler", "Bull", "The Weber Show", "Nash Bridges", "Dark Angel", "Just Shoot Me!", "Watching Ellie", "Philly", "Presidio Med", "The Division", "NYPD Blue", "Monk", "Criminal Minds", "Trust Me", "House", "NCIS: Los Angeles", "Intelligence", "The Mentalist", "The Hillywood Show", "Rizzoli & Isles" and "Con Man".

She played Sarah Lennox in the movie "Transformers (2007)".

Some other movies she appeared in are "Jerry Maguire (1996)", "The Truth About Juliet (1998)", "Avalon: Beyond the Abyss (1999)", "What Planet Are You From? (2000)", "Noriega: God's Favorite (2000)", "Fidel (2002)", "Dragonfly (2002)", "McBride: Dogged (2007)", "Love's Unending Legacy (2007)", "Love's Unfolding Dream (2007)", "The Chosen One (2010)", "The Producer (2012)" and "The Devil's Dolls (2016)".

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