杰丝·威克斯勒（Jessica “Jess” Weixler，1981 年 6 月 8 日出生）是一位美国女演员，迄今为止最出名的是喜剧恐怖电影《牙齿》和喜剧《大坏游泳》的主角。她于 1999 年毕业于肯塔基州路易斯维尔的阿瑟顿高中，在那里她还参加了瓦尔登剧院音乐学院课程，并在 The River City Players 表演小组和室内歌手合唱团中被评为“最有才华”，然后就读于茱莉亚音乐学院。

Jessica "Jess" Weixler (born June 8, 1981) is an American actress, best known to date as the lead in the comedy-horror film Teeth and the comedy The Big Bad Swim. She graduated in 1999 from Atherton High School in Louisville, Kentucky, where she also attended the Walden Theatre Conservatory Program and was in The River City Players acting group and in the Chamber Singers choral group and was voted "most talented", and then attended Juilliard.

She was nominated for a Breakthrough Award at the Gotham Awards in 2007 and won the Special Jury Prize in Dramatic category For a juicy and jaw-dropping performance at the Sundance Film Festival in 2007 both for her role in Teeth. She also appeared in the TV series Law & Order: Criminal Intent. In January 2009, she was named by New York Magazine as the "New Indie Queen" of the year and one of the fourteen "New Yorkers you need to know." She currently lives in Carroll Gardens, Brooklyn, New York.

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