Frank Grillo is known for his roles as Hart Jessup (1996-1999) on the CBS TV soap drama "Guiding Light (1952-2009)" and as Nick Savrinn (2005-2006) on the Fox TV show "Prison Break (2005-2009, 2017)".

He played Alvey Kulina on the Audience Network TV show "Kingdom (2014-)".

Some other TV shows he appeared on are "Silk Stalkings", "Law & Order: Special Victims Unit", "For the People", "The Shield", "The District", "CSI: Crime Scene Investigation", "Without a Trace", "Las Vegas", "The Kill Point", "CSI: NY", "The Gates", "Law & Order: Special Victims Unit" and "Breakout Kings".

He appeared in movies like "The Mambo Kings (1992)", "The Sweetest Thing (2003)", "Hunter: Return to Justice (2004)", ""Warrior (2011)", "The Grey (2012)", "End of Watch (2012)", "Zero Dark Thirty (2012)", "Captain America: The Winter Soldier(2014)", "The Purge: Anarchy (2014)" and "Captain America: Civil War (2016)".

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