Issa López is a Mexican director, writer and producer. Twelve Spanish language features have been produced from her scripts, four of them directed by herself. She has won several literary awards, including the National Novel Award granted by Mexico's Institute of Fine Arts and Literature in 2007.

In 2017, Tigers Are Not Afraid (Vuelven in Spanish) premiered at Fantastic Fest, in Austin, Texas. Written and directed by López, the film received the Best Horror Director Award, and went on to collect fifty-one awards in film festivals around the world, three Diosas de Plata, including Best Picture and Best Director, and received ten Ariel Awards nominations, of which it won two. The film earned multiple positive reviews by major trades and critics, and a rating of 97% on Rotten Tomatoes. Currently, López is developing projects with Guillermo del Toro, Noah Hawley and Jason Blum. She directed and co-wrote all episodes of the fourth installment of HBO's TV series True Detective, which aired in January and February of 2024, as True Detective: Night Country.

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