Sue Thomas is a Deaf woman with the ability to read lips. She moves to Washington, D.C. to begin her new job as an FBI agent and discovers that her new job is not all it's cracked up to be. Due to an out-of-date directory, she accidentally vents her disappointment to Special Agent Jack Hudson, who is impressed by her honesty and tests her skills by having her read a colleague's lips, discovering he is planning a weekend away with a woman. Jack asks Sue to join his Unit of Special Investigators, where she discovers that her new friend Lucy is the girlfriend of Myles, the man Sue saw earlier planning a trip with a different woman.

While trying to protect an Afghan leader, the team loses their primary assassin. But when they think that all hope is lost, another possible assassin is tracked down and put under surveillance, giving the team interesting results.

In the middle of the Christmas season, a mysterious Santa was robbing banks with a few helpers. Bobby tries to present a good image to the press but a determined reporter is eager to attack the FBI. Sue's relationship with her mother comes to a head when her parents stay over.