Dr. Oliver Wolf reluctantly accepts a job at Bronx General Hospital where he's forced to work with a team of interns as they treat a mother who can no longer recognize her children.

When a high school girls' basketball coach faces a debilitating illness, Dr. Wolf must help her reconnect with her body before it's too late. Ericka and Dana treat a frat boy who sees dragons.

A member of a biker gang seeks out Dr. Wolf's help as he grapples with life-threatening memory loss. The interns are tasked to help a young girl struggling with mysterious seizures.

When a bloody bride stumbles into Bronx General, Wolf races against the clock to save her and her missing husband. Ericka and Jacob fight to keep a John Doe patient in their care.

Wolf must help a Marine grapple with mysterious symptoms before the birth of his child.

When an artist refuses to paint for his upcoming show, Dr. Wolf and his team must figure out why. Dr. Pierce goes into uncharted territory with a patient.

Dr. Wolf and his team face their biggest challenge yet when an apartment building collapses in the Bronx.

Dr. Wolf meets a pastor dealing with mysterious visions. The interns grapple with the fallout from the building collapse.