The Pierre Berton Show was a television show hosted by Pierre Berton. It ran from 1962 to 1973, and Berton regularly interviewed important artists, actors, and other public figures. His iconic interviews included Malcolm X in 1965, Lenny Bruce in 1966, and the only known interview with Bruce Lee in 1971.

When CTV launched, a Pierre Berton show quickly followed, aiming to compete with CBC's late-night news. Initially on CTV, it later shifted to CHCH Hamilton due to scheduling conflicts, continuing its acclaimed interviews syndicated by Screen Gems. Despite its brief CTV run, it relocated to Hamilton after CTV adjusted its lineup to rival CBC's 11:00 PM news.