Season 0 of Des O'Connor Tonight premiered on April 10, 1982.

Season 1 of Des O'Connor Tonight premiered on October 17, 1977.

Season 2 of Des O'Connor Tonight premiered on September 18, 1978.

Season 3 of Des O'Connor Tonight premiered on January 14, 1980.

Season 4 of Des O'Connor Tonight premiered on October 27, 1980.

Season 5 of Des O'Connor Tonight premiered on September 28, 1981.

Season 6 of Des O'Connor Tonight premiered on November 1, 1982.

Season 7 of Des O'Connor Tonight premiered on November 1, 1983.

Season 8 of Des O'Connor Tonight premiered on September 11, 1984.

Season 9 of Des O'Connor Tonight premiered on October 8, 1985.

Season 10 of Des O'Connor Tonight premiered on October 14, 1986.

Season 11 of Des O'Connor Tonight premiered on October 21, 1987.

Season 12 of Des O'Connor Tonight premiered on October 26, 1988.

Season 13 of Des O'Connor Tonight premiered on October 25, 1989.

Season 14 of Des O'Connor Tonight premiered on October 31, 1990.

Season 15 of Des O'Connor Tonight premiered on October 16, 1991.

Season 16 of Des O'Connor Tonight premiered on October 7, 1992.

Season 17 of Des O'Connor Tonight premiered on November 17, 1993.

Season 18 of Des O'Connor Tonight premiered on November 30, 1994.

Season 19 of Des O'Connor Tonight premiered on December 13, 1995.

Season 20 of Des O'Connor Tonight premiered on December 11, 1996.

Season 21 of Des O'Connor Tonight premiered on December 3, 1997.

Season 22 of Des O'Connor Tonight premiered on August 5, 1998.

Season 23 of Des O'Connor Tonight premiered on July 2, 1999.

Season 24 of Des O'Connor Tonight premiered on December 28, 2000.

Season 25 of Des O'Connor Tonight premiered on December 24, 2001.

Season 26 of Des O'Connor Tonight premiered on April 6, 2002.

Season 27 of Des O'Connor Tonight premiered on August 25, 2003.