Seth and Kate stage a heist, while Gonzalez endures frightening visions that lead to a grisly discovery, and back at the Twister, Malvado's plans are set into motion by Carlo's emergence from the labyrinth.

Kate hunts down Scott in Bethel before he can exact revenge. In Houston, Richie and Santanico find themselves deep in the flesh trade, while Seth tries to get back in Uncle Eddie’s good graces.

Richie and Seth make peace and team up to look for Malvado's headquarters. Meanwhile, Carlos kidnaps Santanico; and Kate tries to save her brother with help from Freddie.

Uncle Eddie helps Rich and Seth make a plan to complete Santanico's revenge. Meanwhile, Freddie and Kate encounter an unexpected foe following Malvado's attack.

Santanico confronts Malvado with Seth's help; Richie and Kate must stop Carlos and Scott from overturning the ancient prophecy and taking control of a powerful evil.