A game called El Taxi Loco introduces the viewers to the celebrities competing in "Celebrity Mole: Yucatan." Other games include "Salespeople Game" and "Moon Over Yucatan." $31,000 is successfully added to the pot, however, the celebrities wonder if possible sabotage by the mole might have kept them from earning more. Two celebrities successfully earn exemptions.

A piñata game features the celebrities in a fierce battle for both money in the pot and a prized exemption. The classic game in which the celebrities must pick one of their own to receive an exemption or lose money from the pot is revived with the same result as the previous installment: money is lost from the pot. Tensions flare as players are accused of deliberate sabotage leading to loss of money for the pot. The second execution ceremony has a surprising result.

The celebrities play a game called "Clucks for Bucks'" in which they must catch chickens that match numbered hats. A maze game proves a challenging taks for most of the celebrities. One celebrity is given a rather fattening opportunity at an exemption. As suspicions continue to grow, a third celebrity is executed and sent home.

The executed players return for a game called "Tequila Shooters" in which the celebrities try to deliver wine while being pelted with dodgeballs. Afterwards, a gross food challenge sends most reeling, but one is able to stomach it. Later, the celebrities take part an artistic game that leads to some of the strangest artwork ever. The quiz results in a tie, but the result is still the same: a fourth celebrity is executed and sent home.

The celebrities are sent on a shopping spree that involves donkeys and reading clues in Spanish. The individual effort nature of the game leads some players to wonder if others are sabotaging by not providing proper information. The celebrities are taken to a school, where they participate in a Night School game that tests them on basic elementary school knowledge. After some correct answers and embarrassing mistakes, one celebrity is given a twisted exemption offer. The celebrities then attempt to identify the noses of other well-known celebrities and then a fifth is sent home.

Mark Curry dons a cape, as promised and gives himself a superhero nickname, "Mr. Danger." The celebrities take part in aquatic games. Later, one celebrity is called out for breaking the rules. The three remaining celebrities take the final twenty question quiz to determine who wins, who loses and who is the mole.