开朗率真的于小强(闫妮饰)，由于丈夫出轨而选择离婚。离婚后一无所有的于小强，遇到比自己小6岁的电脑维修师鲍家明(胡歌饰)。鲍家明是安徽茶商的后代，他不要过父母安排的人生，独闯上海，成为一名电脑工程师。于小强和鲍家明在各自人生的最低谷，相遇相识并开始重新创业。但是，这段“姐弟恋”却不被看好，家明家庭反对。特别是当于小强怀有前夫的孩子的时候，鲍家明站出来愿意给无辜孩子当父亲！美好的爱情，让这对在年龄、经历都相差甚远的人结为夫妻。婚后，他们同甘共苦，用奋斗和真情克服重重难关，于小强蜕变成人人都爱的好媳妇，鲍家明也成为一个有担当有责任感的男人。

Since Yu Xiaoqiang married Liu Guangyao seven years ago, she's settled into the quiet life of a regular housewife. Her life is turned upside down when one day, computer engineer Bao Jiaming comes to her house to fix a computer and she discovers that Guangyao is having an affair with a clothing designer he works with, Lan Xin. Meanwhile, Jiaming puts everything he has into starting a company with a friend, but in the midst of that, his girlfriend Du Du breaks up with him and financially cripples the project. At the lowest points in their lives, Xiaoqiang and Jiaming find comfort in each other's friendship and start to develop feelings for one another.