Worlds collide when a vengeance-obsessed young woman from the other side of the tracks captures the attention of two well-off friends.

Based on the Pretty Little Liars series of young adult novels by Sara Shepard, the series follows the lives of four girls — Spencer, Hanna, Aria, and Emily — whose clique falls apart after the disappearance of their queen bee, Alison. One year later, they begin receiving messages from someone using the name "A" who threatens to expose their secrets — including long-hidden ones they thought only Alison knew.

Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital's surgical unit. Unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.

When three working class kids enroll in the most exclusive school in Spain, the clash between the wealthy and the poor students leads to tragedy.

Bored and unhappy as the Lord of Hell, Lucifer Morningstar abandoned his throne and retired to Los Angeles, where he has teamed up with LAPD detective Chloe Decker to take down criminals. But the longer he's away from the underworld, the greater the threat that the worst of humanity could escape.

Pablo is a man with a natural ability for business. Early in his life, Pablo is introduced to the business of cocaine and the power it yields. A young life of crime lands Pablo in and out of jail as he builds his criminal empire. Pablo expands his power through politics but it is not long before his conflicts as a Congressman and a drug lord collide. Pablo has his enemies executed, but not before the United States activates its own war on the Medellin cartel.

When they were boys, Sam and Dean Winchester lost their mother to a mysterious and demonic supernatural force. Subsequently, their father raised them to be soldiers. He taught them about the paranormal evil that lives in the dark corners and on the back roads of America ... and he taught them how to kill it. Now, the Winchester brothers crisscross the country in their '67 Chevy Impala, battling every kind of supernatural threat they encounter along the way.

Set in Springfield, the average American town, the show focuses on the antics and everyday adventures of the Simpson family; Homer, Marge, Bart, Lisa and Maggie, as well as a virtual cast of thousands. Since the beginning, the series has been a pop culture icon, attracting hundreds of celebrities to guest star. The show has also made name for itself in its fearless satirical take on politics, media and American life in general.